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(214 customer reviews)


Apetamin is a vitamin syrup that’s claimed to aid weight gain. It contains cyproheptadine hydrochloride, a prescription-only antihistamine .Apetamin is a drug used for appetite stimulation and weight gain that contains a prescription medication and different vitamins. Apetamin Syrup belongs to a group of medicines called antihistamines. It is used in the treatment of various allergic conditions.

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APETAMIN 200ml est un sirop vitaminé de prise le poids et masse musculaire. Homme comme Femme, devenez plantureux ! Apetamin is a vitamin syrup that’s claimed to aid weight gain. It contains cyproheptadine hydrochloride, a prescription-only antihistamine . Apetamin is a drug used for appetite stimulation and weight gain that contains a prescription medication and different vitamins. Apetamin Syrup belongs to a group of medicines called antihistamines. It is used in the treatment of various allergic conditions.

What is Apetamin?

Apetamin is a vitamin syrup that’s marketed as a weight gain supplement. It was developed by TIL Healthcare PVT, a pharmaceutical company based in India.

According to manufacturing labels, 1 teaspoon (5 ml) of Apetamin syrup contains:

  • Cyproheptadine hydrochloride: 2 mg
  • L-lysine hydrochloride: 150 mg
  • Pyridoxine (vitamin B6) hydrochloride: 1 mg
  • Thiamine (vitamin B1) hydrochloride: 2 mg
  • Nicotinamide (vitamin B3): 15 mg
  • Dexpanthenol (an alternative form of vitamin B5): 4.5 mg

The combination of lysine, vitamins, and cyproheptadine is claimed to aid weight gain, though only the last one has been shown to potentially increase appetite as a side effect (1Trusted Source2Trusted Source).

However, cyproheptadine hydrochloride is mainly used as an antihistamine, a type of drug that eases allergy symptoms like runny nose, itching, hives, and watery eyes by blocking histamine, a substance your body makes when it has an allergic reaction (3).

Apetamin is available in syrup and tablet form. The syrup generally contains vitamins and lysine, whereas the tablets only include cyproheptadine hydrochloride.

The supplement is not approved by the Food and Drug Administration (FDA) due to safety and effectiveness concerns, and it’s illegal to sell it in the United States and many other countries (4).

Nevertheless, some small websites continue to sell Apetamin illegally.

SUMMARYApetamin is marketed as a supplement that helps you gain weight by increasing your appetite.

How does it work?

Apetamin may promote weight gain because it contains cyproheptadine hydrochloride, a powerful antihistamine whose side effects include increased appetite.

Though it’s unclear how this substance increases appetite, several theories exist.

First, cyproheptadine hydrochloride appears to increase levels of insulin-like growth factor (IGF-1) in underweight children. IGF-1 is a type of hormone linked to weight gain (5Trusted Source).

In addition, it seems to act on the hypothalamus, a small section of your brain that regulates appetite, food intake, hormones, and many other biological functions (6Trusted Source).

Still, more studies are needed to understand how cyproheptadine hydrochloride may increase appetite and lead to weight gain.

In addition, Apetamin syrup contains the amino acid l-lysine, which has been linked to increased appetite in animal studies. Nevertheless, human studies are needed (7Trusted Source).

Is it effective for weight gain?

Though research on Apetamin and weight gain is lacking, several studies found that cyproheptadine hydrochloride, its main ingredient, may aid weight gain in people who have lost their appetite and are at risk of malnutrition.

Additionally, a 12-week study in 16 children and adolescents with cystic fibrosis (a genetic disorder that may feature a loss of appetite) noted that taking cyproheptadine hydrochloride daily led to significant increases in weight, compared to a placebo (1Trusted Source).

A review of 46 studies in people with varying conditions observed that the substance was well tolerated and helped underweight individuals gain weight. However, it did not help people with progressive diseases, such as HIV and cancer (8Trusted Source).

While cyproheptadine may benefit those at risk of malnutrition, it could lead to excessive weight gain in overweight people or those with a healthy weight.

For example, a study in 499 people from the Democratic Republic of Congo revealed that 73% of participants were misusing cyproheptadine and at risk of obesity (9Trusted Source).

In short, while cyproheptadine hydrochloride may help underweight people gain weight, it may put the average person at risk of obesity, which is a significant problem worldwide.

SUMMARYApetamin contains cyproheptadine hydrochloride, which may increase appetite as a side effect. In theory, it may do so by raising levels of IGF-1 and acting on the area of your brain that controls appetite and food intake.

Is Apetamin legal?

Selling Apetamin is illegal in many countries, including the United States.

That’s because it contains cyproheptadine hydrochloride, an antihistamine that is only available with a prescription in the United States due to safety concerns. Misusing this substance may cause serious outcomes, such as liver failure and death (9Trusted Source10).

In addition, Apetamin is not approved or regulated by the FDA, which means that Apetamin products may not truly contain what is listed on the label (11Trusted Source12Trusted Source).

The FDA has issued seizure notices and warnings on importing Apetamin and other vitamin syrups containing cyproheptadine due to safety and effectiveness concerns (4).

SUMMARYThe sale of Apetamin is banned in many countries, including the United States, as it contains cyproheptadine hydrochloride, a prescription-only medication.


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Potential side effects of Apetamin

Apetamin has many safety concerns and is illegal in many countries, which is why reputable stores in the United States don’t sell it.

Still, people manage to get their hands on illegally imported Apetamin through small websites, classified listings, and social media outlets.

A major concern is that it contains cyproheptadine hydrochloride, a prescription-only medication that has been linked to various side effects, including (9Trusted Source):

  • sleepiness
  • dizziness
  • tremors
  • irritability
  • blurred vision
  • nausea and diarrhea
  • liver toxicity and failure

In addition, it can interact with alcohol, grapefruit juice, and many drugs, including antidepressants, Parkinson’s disease medications, and other antihistamines (3).

Because Apetamin is imported illegally into the United States, it’s not regulated by the FDA. Thus, it may contain different types or amounts of ingredients than listed on the label (12Trusted Source).

Considering its illegal status in the United States and other countries, as well as its adverse effects, you should avoid trying this supplement.

Instead, speak with your healthcare provider to determine the safest and most effective treatment option if you have trouble gaining weight or a medical condition that reduces your appetite.

SUMMARYApetamin is illegal in the United States and many other countries. Plus, its main ingredient, cyproheptadine hydrochloride, has been linked to serious side effects and is only available with a prescription.

The bottom line

Apetamin is a vitamin syrup that’s claimed to aid weight gain.

It contains cyproheptadine hydrochloride, a prescription-only antihistamine that may increase appetite.

It’s illegal to sell Apetamin in the United States and elsewhere. Plus, the FDA does not regulate it and has issued seizure notices and import warnings.

If you’re looking to gain weight, speak to a dietitian and your healthcare provider to develop a safe and effective plan tailored to your needs, rather than relying on illegal supplements.

How we reviewed this article:


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By Ryan Raman, MS, RD on June 5, 2019

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3 Bottles (200ml), 6 Bottles, 12 Bottles, 25 Bottles (1 Carton), 2 Carton (50 Bottles), 4 Carton ( 100 Bottles)

214 reviews for Apetamin

  1. Sally

    Yes they did increase my appetite. And I’ve gain weight

  2. Jammie

    These work awesome! I saw a difference in 2 weeks as well as others who complimented me..

  3. Torres

    I would suggest these to anyone who cant gain weight on there own

  4. India

    It worked for me

  5. Kyle

    I’m very much please I really look good with my weigh back on.

  6. Stacy

    Thank you I’m trying to get a friend to get some.

  7. Debbie

    They truly work!

  8. Denise

    Was very pleased with my order came very fast

  9. Anne

    Very Happy Customer

  10. Barbara

    Have ordered this for my husband and he is gaining weight. Good product.

  11. Clayton

    I have used this product before. It does help you gain weight. Thanks

  12. Michelle

    Good product 👍🏻

  13. Megane

    I bought this for my husband who was losing weight from chemo treatments.It was really worth it.

  14. Jenny

    I love the syrup it works for me

  15. Smith

    The product was for my mother she has gained five pounds

  16. Betty

    i gave this pills to my daughter so she can gain some weight she is so skinny thanks. It works

  17. Alice

    I was very pleased with product.

  18. Monica

    Very satisfied !

  19. Lilo

    Works great

  20. Cycy

    Very good!

  21. Plies


  22. Laura

    This is a very good weight gain formula!

  23. Graham

    As soon as I take it, 30 minutes later my stomach starts to growl like I haven’t eaten anything all day!! It boosts your appetite.

  24. Suzy

    Great 👍🏻 I’ve been on it for three weeks and already eating more than I ever expected.

  25. Vanessa

    It is incredible. I didn’t think it was possible!! No SIDE EFFECTS AT ALL!!

  26. Olga

    will order more in a week and continue on it until my goal is achieved!! Good luck!!

  27. Alex

    Gain weight syrups are good for those having problems trying to eat and gain. They do Work.

  28. Sophia

    I Give them 5 Stars i very happy of what i saw.

  29. David

    i am happy with this syrup it dose work, just eat normal meals when you take it. that’s what i did i went from 110 pounds up to 125 pounds so that was good for me.

  30. Marie

    When you get this product you start taking it. Do your self a big favor take a picture of what you look like. after a month on gain weight pills take another pictures and compare it to your old picture. it might help you to see the difference and all.

  31. Nicole

    Recommend this product to anyone that is having trouble gaining weight.

  32. Kendrick

    Its 100% natural without any side effects.

  33. Ariana

    It really works!!!

  34. Kelly

    This product is really great it increased my appetite and I gained the weight I wanted..

  35. Steve

    I have purchased my second bottle

  36. Landry

    It’s truly a great product I love it.

  37. Katty

    At first I thought am just wasting my money ,but believe me it was a better decision I ever took.

  38. Sonita

    This syrup opened up my appetite and I gained some kilos

  39. April

    It was not wast of money, it worth it .

  40. Simi

    it . I wish people who also struggling to gain some kilos can try this Syrup.

  41. Louisa

    I can not wait to order another bottle.

  42. Sarah

    I can’t wait to qain Some kilos again. I really got my answers for my long time problem.

  43. Claudia

    My husband at first was not trusting this pills said its just wast of time and money,but now he is the one who is praising this pills every now and then.

  44. Jay

    Works well

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